منابع مشابه
Anti-lipoapoptotic effects of Alisma orientalis extract on non-esterified fatty acid-induced HepG2 cells
BACKGROUND Liver steatosis was caused by lipid accumulation in the liver. Alisma orientale (AO) is recognized as a promising candidate with therapeutic efficacy for the treatment of nonalcoholic fatty liver disease (NAFLD). HepG2 hepatocyte cell line is commonly used for liver disease cell model. METHOD The HepG2 cells were cultured with the NEFAs mixture (oleic and palmitic acids, 2:1 ratio)...
متن کاملEffect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro.
BACKGROUND NEFA plays numerous roles in the metabolism of glucose, lipids, and proteins. A number of experimental studies have shown that NEFA may have an important role in fatty acid metabolism in the liver, especially in dairy cows that experience negative energy balance (NEB) during early lactation. METHODS In this study, using fluorescent quantitative RT-PCR, ELISA, and primary hepatocyte...
متن کاملNon-esterified fatty acid and glycerol kinetics and fatty acid re-esterification in goats during early lactation.
Non-esterified fatty acid (NEFA) and glycerol kinetics were studied in lactating goats to gain insight into the mechanisms by which animals in early lactation can initially mobilize and later replenish body fat reserves. Kinetic measurements were made at days 10, 38 and 76 post-partum in ten multiparous lactating does. Plasma NEFA concentrations and NEFA entry rate decreased as lactation advanc...
متن کاملFatty Acid Profile of CE in HSV - I - infected Human Arterial SMC Fatty acid esterified
Herpesviruses have been implicated as etiologic factors in the pathogenesis of human arteriosclerosis. We have examined the pathobiological effects of human herpes simplex virus (HSV-1) infection in influencing lipid accumulation and metabolism in human and bovine arterial smooth muscle cells (SMC). Significantly greater amounts of saturated cholesteryl esters (CE) and triacylglycerols (TG) acc...
متن کاملTurnover modeling of non-esterified fatty acids in rats after multiple intravenous infusions of nicotinic acid.
The objective of this investigation was to use a pharmacokinetic (PK)/pharmacodynamic (PD) approach to describe and evaluate a PK model of nicotinic acid (NiAc) in guinea pigs and a PD feedback model of changes in non-esterified fatty acid (NEFA) concentrations in rats following multiple intravenous infusions of NiAc at different rates and durations of inhouse and literature (NEFA after extrava...
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ژورنال
عنوان ژورنال: Folia Endocrinologica Japonica
سال: 1964
ISSN: 0029-0661
DOI: 10.1507/endocrine1927.39.11_1052